A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
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Spatial framework facilitates cooperation in a very social dilemma: empirical proof from a bacterial community
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As a individual, I contain the biblical assignment to discover and use almost everything in generation for the good thing about my neighbour. I don't knowledge any conflict concerning faith and science. On the contrary, my faith stimulates me to perform science, to generally be open up-minded on earth.’
I am able to rarely consider how I, for a geneticist, would have the capacity to study elementary physics, let alone compete at the best. How did you go over it?
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design in 2005. (nl)
SMC complexes can move Bodily roadblocks bigger than their ring sizing, indicating a nontopological system for DNA loop extrusion
We use nanofabricated microfluidic constructions to sample spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this assess the fundamental function of spatial confinement in the molecular and cellular amount. Our tasks include the next:
Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim of the pore is highlighted in purple, along with a 3D rendering with the motion with the DNA rod is displayed.
The rotors harness energy from the nanoscale water and ion move that is definitely produced by a static chemical or electrochemical potential gradient from the nanopore, that happen to be set up via a salt gradient or applied voltage, respectively. These synthetic nanoengines self-Arrange and work autonomously in physiological problems, suggesting approaches to constructing Electricity-transducing motors at nanoscale interfaces.
Quite neat, but that wasn’t actually wherever my desire lay. I planned to pioneer And that i had the feeling that was now not possible, because the most appealing essential insights had presently been uncovered. But my subject experienced developed several enjoyable new tools to measure personal molecules. I made a decision which i planned to utilize this to biology, to look at it from a physical perspective.’
Tests pseudotopological and nontopological designs for SMC-pushed DNA loop extrusion versus roadblock-traversal experiments
A lot of new https://www.ceesdekker.net phenomena had been discovered, and he and his exploration group recognized a leading situation On this industry of investigation. Dekker and his study team discovered new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they had been the 1st to construct a transistor dependant on just one nanotube molecule.
One example is, we consider the nucleopore intricate, a gateway among the cell nucleus plus the cytoplasm. This is an extremely complex procedure and for that reason tough to study inside of a cell, so we use biomimetics. We reconstruct holes and after that insert unique aspects in the nucleopore complex to review transport by it at the single-molecule amount.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart structure in 2005. (nl)